24 research outputs found

    Constrained K-Means Classification

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    Classification-via-clustering (CvC) is a widely used method, using a clustering procedure to perform classification tasks. In this paper, a novel K-Means-based CvC algorithm is presented, analysed and evaluated. Two additional techniques are employed to reduce the effects of the limitations of K-Means. A hypercube of constraints is defined for each centroid and weights are acquired for each attribute of each class, for the use of a weighted Euclidean distance as a similarity criterion in the clustering procedure. Experiments are made with 42 well–known classification datasets. The experimental results demonstrate that the proposed algorithm outperforms CvC with simple K-Means

    Cyra: A model-driven cyber range assurance platform

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    Digital technologies are facilitating our daily activities, and thus leading to the social transformation with the upcoming 5G communications and the Internet of Things. However, mainstream and sophisticated attacks are remaining a threat, both for individuals and organisations. Cyber Range emerges as a promising solution to effectively train people in cybersecurity aspects. A Training Programme is considered adequate only if it can adapt to the scope of the attacks they cover and if the trainees apply the learning material to the operational system. Therefore, this study introduces the model-driven CYber Range Assurance platform (CYRA). The solution allows a trainee to be trained for known and new cyber-attacks by adapting to the continuously evolving threat landscape and examines if the trainees transfer the acquired knowledge to the working environment. Furthermore, this paper presents a use case on an operational backend ICT system, showing how the CYRA platform was utilised to increase the security posture of the organisation

    Gut Barrier Disruption Secondary to Radiofrequency-Assisted Liver Parenchyma Resection in a Porcine Model

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    Background: Radiofrequency-assisted liver resection (RF-LR) techniques minimize intraoperative blood loss, while avoiding the Pringle maneuver. Both surgical excision and radiofrequency ablation of liver parenchyma compromise gut barrier function with subsequent bacterial translocation. The present study sought to investigate in a porcine model the impact of two RF-LR techniques on the integrity and inflammatory response of the gut barrier. Methods: Twenty-four pigs were subjected to either (a) partial hepatectomy (PH) employing the “sequential coagulate-cut” technique using a monopolar electrode (SCC group), the one using the bipolar Habib-4X device (group H), or the “crush-clamp” technique (group CC) or (b) sham operation (group Sham). At 48-h post-operation, ileal tissue was excised to be subjected to histopathologic examination, histomorphometric analysis, and immunohistochemical assessment of the mitotic and apoptotic activities and the expression of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), and nuclear factor-κB (NFκΒ). Results: Histopathologic score increased in all PH groups, being higher in group SCC, while lower in group H. Villous height decreased in group SCC only. Mitotic index decreased, while apoptotic index increased in all PH groups. An increase in tissue expression score was noted for IL-6 in group CC, for TNFα in all PH groups, being lower in group H compared to group CC, and for NFκB in all PH groups. Conclusions: The Habib-4X technique for liver resection proved to preserve the integrity of gut barrier, being less injurious in the intestinal mucosa compared to the SCC and CC techniques. © 2022, The Society for Surgery of the Alimentary Tract
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